The more data that emerges on galectin-3, the more we see how it serves as the master regulator of our health and disease axis. Hospital affiliations include Hoag Memorial Hospital Presbyterian. Effect of a proprietary Magnolia and Phellodendron extract on weight management: a pilot, double-blind, placebo-controlled clinical trial. Luckily, a large and fast-growing body of research has given us a specific therapeutic target to achieve this goal: the biological protein galectin-3. Furthermore, its best to speak with your healthcare provider before taking magnolia bark supplements, especially if youre currently using other supplements or medications. All rights reserved. Copyright 2023 The Botanical Institute |, https://doi.org/10.1016/j.neuropharm.2012.06.031, https://www.henriettes-herb.com/eclectic/cook/MAGNOLIA_GLAUCA.htm, https://botanical.com/botanical/mgmh/m/magnol03.html#oth, https://www.christopherhobbs.com/webdocs/class-handouts/various/Healing-Sleep-Breitenbush.pdf, https://doi.org/10.3858/emm.2008.40.6.617, https://www.henriettes-herb.com/eclectic/dmna/magnolia.html#glau-bot-hist, https://static1.squarespace.com/static/55636a78e4b0658666cb6541/t/5eac6913be207478cdbd2980/1588357463831/Perky+Calm+Alert+Slides.pdf, https://www.ncbi.nlm.nih.gov/books/NBK537103/, https://doi.org/10.1111/j.1476-5381.2012.02010.x, https://doi.org/10.1007/s00284-020-02056-6, https://doi.org/10.1142/S0192415X13500389. At the same time, immune system under-reactions could leave you catching every cold, flu, or other bug thats going around. In Kampo or traditional Japanese medicine, magnolia bark was also used for gastrointestinal support. But as the saying goes, no one wins in war. And when you pair honokiol with MCP, the antioxidant and anti-inflammatory effects of both increase significantly, offering more stress relief for you. Magnolia bark benefits the body through its ability to reduce anxiety, lower cortisol, and naturally regulate stress. When cortisol levels decrease, it suggests that overall stress has also decreased. Save my name, email, and website in this browser for the next time I comment. The shift from survival to wellness and harmony serves as the foundation of a truly holistic model of medicine, which we apply extensively in our clinic, Amitabha Medical Clinic in Santa Rosa, California. Other worthwhile measures include exercise, meditation, eliminating caffeine (from all sources), cognitive behavioral therapy, journaling and taking a news fast by avoiding the daily onslaught of (mostly bad) news online, on television and in newspapers and magazines. One of the extracts most prominent effects was a reduction in inflammation. In another in vitro study, honokiol showed promising effects on oral cancer cells. Retrieved from: https://static1.squarespace.com/static/55636a78e4b0658666cb6541/t/5eac6913be207478cdbd2980/1588357463831/Perky+Calm+Alert+Slides.pdf, Ogobuiro I, Gonzales J, Tuma F. (2021) Physiology, Gastrointestinal. (2017). Magnolia essential oil is known for stimulating the lymphatic system and helps in making the liver to function properly and help in toxins elimination. In order to stay ahead of the disease, we have to outwit it at every turn. Magnolol, a major bioactive constituent of the bark of Magnolia officinalis, induces sleep via the benzodiazepine site of GABA(A) receptor in mice. Journal of the International Society of Sports Nutrition, 10(1), 37. https://doi.org/10.1186/1550-2783-10-37, Tian, H., Zhao, L., Zhang, Q., Zhang, Y., Mao, X., Wang, J., Li, T., Li, J., You, Z., Ruan, Q., & Jiang, L. (2020). Magnolia barks effects on sleep appear to be closely connected to the activity of the GABA(A) receptors in the central nervous system. This not only includes brain disorders like Alzheimers disease but also conditions like stress, anxiety, mood disorders, and depression (23). Once it matures, the height can reach up to 100 feet and the canopy can spread at up to 70 feet. Exception of use under qualified healthcare practitioner supervision. MAGNOLIA BARK MAY HELP SUPPORT RELAXATION AND STRESS MANAGEMENT* One of main Magnolia Bark benefits is its unique calming effects. The herb combination reduced salivary cortisol, a marker of stress, by 18% in comparison to the placebo. Use a combination of these stress-reducing methods to calm down your mind and body no matter what life throws at you. It is also commonly used to support gastrointestinal health. Researchers noted that the extract was enriched with one of magnolia barks active constituents, honokiol. Among them, magnolol and honokiol are the main nutrients in magnolia bark with the most medicinal value. Science. In such cases our first instincts, as well as prevailing medical standards, call to arms an epic battle. Therefore, the effects cannot be credited to the tree bark alone. White oak bark, scientifically known as Quercus alba, translates to "fine tree." Historically used to remedy a long list of conditions, this ingredient is mainly added to washes, baths, teas, tinctures, and other infusions. Science. Given that cancer is a disease characterized by abnormal cell division and growth, the ability to regulate cellular pathways is beneficial (16). Siobhan is a herbal researcher and writer. Magnolia helps in preventing fat from building up around the liver. Some researchers believe that these effects are due to honokiol, a natural compound in the bark. In fact, magnolia bark is thought to be one of the best herbs for sleep. Magnolia barks scientific name is Magnolia officinalis. A honokiol-enriched Magnolia officinalis Rehder & E.H. Wilson. The tree was later transported and cultivated in England. With strict editorial sourcing guidelines, we only link to academic research institutions, reputable media sites and, when research is available, medically peer-reviewed studies. One possible concern is its potential to interact with other supplements or medications. It is the most effective treatment I know. For digestive problems, magnolia bark. are clickable links to medically peer-reviewed studies. Later, it was described in many famous Chinese medical texts such as the "Jingui Yaolue" and the "Shanghan Lun" (ca. In traditional Chinese medicine, magnolia bark is often harvested by being peeled or cut away from the tree. The same study observed that the same dose increased REM (rapid eye movement) and non-REM sleep. Current microbiology, 77(9), 24132421. Exercise also helps regulate your bodys stress responses so you become less reactive when faced with stressors. Magnesium supplements can also interact with other drugs and change how they work in your body. Exceeding the recommended daily limit of magnesium can lead to diarrhea, nausea, stomach cramps, and heart problems. Plus, long-term stress adds an extra strain on your body. magnolia bark. The bark of Magnolia oficinalis has been used in traditional Chinese medicine for centuries to address anxiety and nervous tension and to promote sleep. Researchers believe magnolia barks ability to activate specific proteins was responsible for the anti-cancer effects. Benefit 5 - Brain Health Healthy sleep is essential for cognitive performance. Magnolia trees are very long-lived. Nutrition journal, 7, 11. https://doi.org/10.1186/1475-2891-7-11. The bark is harvested from April to June where it is then dried in shade. Here is a closer look at some of the potential benefits of magnolia bark. But you can take specific steps to help your mind and body calm down even in the face of non-stop stressors. Dietary Supplementation With Magnolia Bark Extract Alters Chicken Intestinal Metabolite Levels. Balanced bacteria in the gut promotes healthy digestion, as well as improved mental health. Retrieved from: https://www.christopherhobbs.com/webdocs/class-handouts/various/Healing-Sleep-Breitenbush.pdf, Hu, J., Chen, L. J., Liu, L., Chen, X., Chen, P. L., Yang, G., Hou, W. L., Tang, M. H., Zhang, F., Wang, X. H., Zhao, X., & Wei, Y. Q. Healthy eating: When youre feeling stressed, your instinct may be to grab for sweet, salty, fatty foods but those can add to your bodys stress load. This article reviews the science-supported benefits and side effects of magnolia bark. It is especially effective when paired with ginger. , Additionally, since one use of magnolia bark is to help in sleeping, you should not take it alongside other anti-anxiety drugs or sleeping pills. This is how we can shift out of survival mode, and into a state of health, wellness and longevity. Both shade and ornamental tree, the California sycamore is large and grows fast, so make sure that you have enough space in your property. Amazon.com: LES Labs Cortisol Health - Stress Relief, Balanced Cortisol Response, Relaxation & Deep Sleep - Phosphatidylserine, Magnesium, Magnolia Bark, Rhodiola Rosea & Ashwagandha - 60 Capsules : Health & Household Note that the numbers in parentheses (1, 2, etc.) Retrieved from: https://botanical.com/botanical/mgmh/m/magnol03.html#oth, Hobbs, C, Ph.D., L.Ac., AHG. Safety and Toxicology of Magnolol and Honokiol. Chewing gum with magnolia bark extract may promote better breath and gum health. Research shows that both magnolol and honokiol are, by nature: The extract of the magnolia bark has been used for thousands of years in traditional Chinese and Japanese medicine. It Starts in the Kitchen, Read New patients are welcome. Effect of Magnolia officinalis and Phellodendron amurense (Relora) on cortisol and psychological mood state in moderately stressed subjects. Magnolia bark is considered a safe supplement for human consumption. (2020). Healthy foods, especially fruits and vegetables, packed with nutrients and antioxidant compounds help your body cope with the damaging effects of stress. The bark of the magnolia . A study in mice found a magnolol dose of 2.30.9 mg per pound (525 mg per kg) of body weight significantly decreased sleep latency, or the amount of time it takes to fall asleep (27). And since stress triggers galectin-3, the alarm protein, it also sets off inflammation even in your brain. Researchers attributed these effects to honokiols potential to reduce anxiety and stress. https://doi.org/10.3322/caac.21590, Talbott, S. M., Talbott, J. (1999). Magnolia officinalis, also known as magnolia bark, has been widely used in traditional Chinese medicine and has many benefits. Regular yoga practice helps regulate your nervous system and reduces the harmful effects of stress. There are two classical formulas in which magnolia bark is still traditionally used. Effect of a proprietary Magnolia and Phellodendron extract on stress levels in healthy women: a pilot, double-blind, placebo-controlled clinical trial. Research shows that magnolia bark benefits sleep quality. When we address unhealthy galectin-3 expression with proven methods, we effectively treat not just cancer, but numerous life-threatening conditions as well. Researchers reviewed studies of pine pollen, and one study reported side effects of diarrhea, bloating, and loss of appetite. Here are 15 herbs with powerful antiviral properties. Honokiol promotes non-rapid eye movement sleep via the benzodiazepine site of the GABA(A) receptor in mice. Galectin-3 allows tumor cells to stick together, develop blood supply, metastasize and evade the immune system. 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