It is typical for people with an excess amount of hydrogen sulfide gas to have their stools turn black when they take bismuth. Small intestine aspirate and fluid culture. But if we dont have enough of it, one theory is that the body encourages overgrowth of H2S producing bacteria to compensate. And they often actually say, I feel toxic. Its really interesting. Lets go through the checklist that Gary has made, to make sure before you decide its hydrogen sulfide, etc. Things that have helped me are ginger, resolor, and eliminating lots of garlic in the diet. Is it the air from the mouth? Gary Stapleton: Yes, thank you, Dr. Ruscio. So I cant report. But by and large, were having a lot of success based on everything that weve discussed. At least in my opinion, I dont want to paint this picture that if youre struggling with symptoms, that knowing you have hydrogen sulfide SIBO is going to be the one thing thats going to take you from highly symptomatic to totally fine. However, the testing for this is not yet available. The other thing thatat least for right now until we have better dataI just want to again remind the audience of is, a good gut-focused or SIBO-focused clinician should be able to help you navigate this. If this isnt working very efficiently, there may be too much unusable sulfur (leading to sensitivities) and not enough usable sulfur (at the same time leading to deficiencies). And the way that that occurs is, a patient presents and they have chronic postprandial symptoms. Now we go back to the clinician and say, do we have the chronic postprandial symptoms? So then as I read some more, I saw that bismuth can also be used. Supplementing with molybdenum, which is a mineral that helps in sulfur metabolism, can also be very helpful. DrMR: Thats alarming, but not surprising. There are so many symptoms that look like other things. And then, very cautiously and parsimoniously, consider expanding outward to other therapies. Is there increased frequency? I might be getting this wrong. Thanks for that. Now, there are some other things that are shown in the research that Ive never tried, like lactobacillus plantarum LP8. It was actually starting a year ago in spring, thats when the first research studies were coming out with this new technology, and they were finding diarrhea. But theres this new gas which may be able to be tested, to tell about a different type of SIBO: hydrogen sulfide SIBO. Guess what? And I think it was about three years ago I started bringing it in. Dr. Michael Ruscio, DC. The studies right now with fecal transplants in IBS patients have not shown good results and can make someone worse. And this is really disheartening, because then these patients end up getting treated and treated and treated and treated, never to really feel much different or see their labs changed, because they were treating a false positive all the while. Its not a guarantee that almost anyones symptoms are being caused by the gut. So those are my clinical symptoms Ive gathered over time and I just share them. When I see zeros, ones, twos, threes parts per million with glucose, were picking up the phone. Learn more about breath testing here. Additionally, H2S can also result from the bacterial breakdown of matter, and can therefore be produced by humans and animals in their waste and gas. And I really want to underscore that point. Mike. This can help make the diagnosis, but it won't treat the cause. Guests Dr. Allison Siebecker, Gary Stapleton, and I discuss the testing methods available to assess and validate your likelihood of hydrogen sulfide SIBO, and their experiences in the clinic and in the lab, respectively. Yes, it is possible to overdo exercise. So Ive seen that work. There are also studies of using bismuth with antibiotics of your choice, really. Now its also not to say that everything new we should be looking at incredibly circumspectly. Please do not apply any of this information without first speaking with your doctor. This isnt a long-term solution, but if you do have hydrogen sulfide-producing SIBO, it will likely help alleviate symptoms. Its pretty interesting. 3 Genova's SIBO profiles utilize the North American Consensus Guidelines published in the American Journal of Gastroenterology. There are actually a couple of research studies, not about SIBO, that show that link. One was done with Cipro. Three of the livers Phase II Detoxification processes (rendering a toxic molecule less harmful) require sulfur: sulfation, glucoronidation, and glutathione-S-transferase. Studies show that a large percentage of Irritable Bowel Syndrome (IBS) is actually Small Intestinal Bacterial Overgrowth (SIBO). The numbers in the parentheses (1, 2, 3) are clickable links to peer-reviewed scientific papers. Part of which are the ones that Dr. Siebecker highlighted for all of us, and thank you to her. Learn exactly what combinations of prescription and herbal antibiotics and supplements are used to treat the 3 main types of SIBO: Hydrogen, Methane, and Hydrogen Sulfide. 2020 SIBO Surivor | All Rights Reserved. It might be parasites. One is by Thorne and theres another one, Paul Andersons one. But it is tenable to say that almost any symptom could be driven by a problem in the gut. Now, we can begin discussing treatment options. And the noise level about hydrogen sulfide right now is confusing them. Two, if your test is negative, consider hydrogen sulfide. Ive said that many times before. And then the spring again, multiple studies came out, diarrhea. However, you can consider treating for SIBO or presume SIBO, and potentially add some nuance to that treatment that is hydrogen-sulfide-specific. Lets go to some closing thoughts. And as with many that are listening (and those here on this podcast), we always look forward to new technologies, new approaches to evaluating SIBO, and whether or not there are applications to that in treatment. But the problem is its so brand new, hasnt even hit the market yet commercially. EXCESS HYDROGEN SULFIDE . It doesnt matter what were talking about. Your . I think it was originally for blastocystis. Again, Aerodiagnostics is the SIBO lab I use in my clinic. The dose was 524 milligrams, four times a day. It is estimated that the average person will make around 0.6 to 1.8 liters (L) of gas every day. This is currently the gold standard test for bacterial overgrowth. But usually its more like I asked, Do you have irritation when youre urinating? Chew the tab up in your mouth and let it get into your bloodstream via saliva. These are the types of gases that are measured on a breath test. But Clindamycin has a very high C. diff rate. And combine that with there was one study using, I believe, rifaximin, in the treatment of hydrogen sulfide SIBO. But these are the validations. Can we reproduce the event, where we can measure hydrogen sulfide and detect it? Aerodiagnostics, again, is my go-to SIBO lab. Sulfur is also part of the cellular stress response, improving ATP (energy) productionso that cells can carry on normal functions even when under stress. Heres what I think this breaks down to. A low sulfur diet enables the overworked enzymes to play catch-up. Its so simple. And I just looked at all the patterns of all my hydrogen sulfide patients. I recently had the opportunity to sit down with Dr. Greg Nigh a Naturopathic doctor fromPsoriasiswho was able to clearly explain this process, as well as provide some insight as to why he believes that sulfur metabolism plays a role in H2S SIBO. The herb Sparga also helps the body to break down sulphur. Welcome to Dr. Ruscio Radio. And please correct me, Dr. Siebecker or Dr. Ruscio, if Im wrong, but you have to understand, these research centers have a different patient population than the clinician thats in private practice in Nebraska or New Jersey or New York or Florida. So hydrogen sulfide, when its in excess, is a toxic gas, like actually literally toxic. Sulfur is also part of the cellular stress response. But oftentimes there is no one straw. It has nothing to do with flat line. The major components of intestinal gas include oxygen, nitrogen, carbon dioxide, hydrogen, and methane. It might be yeast overgrowth. So just for people, this is not something that Gary is just paying lip service to and not actually doing. How do you know if you have SIBO or dybsosis/ hydrogen sulfide issue? So I just dont want someone to be like, But she said this works for hydrogen sulfide. Its always hit or miss. DrAS: Yeah. There are a number of different reasons why this could occur. There are also some supplement products that have bismuth in there. So their actual digestive and all of these symptoms like the neuralgia and the body pain would get worse, which is unique. Currently, breath tests are the most useful diagnostic test for examining the type and amount of gas produced in the gut. So how do you get bismuth? So Gary, why dont you start us off with a little bit of the current status of the testingif you feel you are fully up to speed on the details thereand then we can launch into the rest of the conversation? Its pretty funny actually. The fact that IBS can produce high levels of hydrogen sulfide in the breath was proven in a study published in the Journal of Breath Research. And Gary, I think you made a good point, which istrying to come back to that process that I outlined earlierfirst, test and if youre not sure if the testing is negative or flat lined, double-check that youve done the test appropriately. Youll have to do it in the office of the provider, which makes it significantly less convenient, because now you have to hang out for three hours at a doctors office. This seems contradictory if the whole issue is low sulfur levels, but again, the problem may be that the body is unable to use the sulfur it receives from food. And Thorne, I think, is Pepti-Guard or something. And most of the lactulose in the United States is a syrup. It seems like nitazoxanide can work on methanogens. Theres a study that used it and it had a very successful rate of treating it. And man, I wish we had been recording earlier because I think of all the good stuff we already talked through before we even started recording this call. Its a number of straws that have to be woven together to have strength and to be able to lead to that improvement that were looking for. High-dose oregano. Im not even going to share any more about that. This was really more like muscle pain, like that idea of fibromyalgia, and not as much joint pain, but more muscle kind of pain. so that cells can carry on normal functions even when under stress. So this really confused both of us. And then when I started going out to our normal time framesa minimum of two weeks, if not a monthand usually a month, then we were starting to see better results. Outdoors, H2S is naturally present in crude petroleum, natural gas, volcanic gases, and hot springs. So we need to validate a flat line first, then go to the secondary questions. And then we further validate on the research that Dr. Siebecker did, that Dr. Ruscio is going to supply, and theyll talk about this in a moment. And then number two, do they have chronic postprandial symptoms? Dr. Allison Siebecker, ND: Diarrhea and constipation. Green tea is well documented with research showing it reduces hydrogen sulfide gas by 30%. Are we in agreement that thats kind of a high-level hierarchy to help organize all these thoughts for people? In addition to this benefit, Epsom salt baths are also great for reducing stress, which can further help with any symptoms you might be experiencing. So maybe its pushing someone towards constipation. However, we are, by and large, diagnosing SIBO based on the tried-and-true, time-tested, globally utilized hydrogen and methane breath testing, where we validate that from a gas perspective. Ive done it before, and so have many clients of Dr. Mike T. Nelsons. This is the baseline approach to healing any GI issuesactually any health issues at all. Pepto-Bismol: Generally given as part of H.pylori treatment, Pepto-Bismol is also known to impact other bacteria. Were there to be the specialists on the diagnostic end. For the high-dose oregano that Im using, Im using the emulsified one thats in a dry tablet form. I see people after theyve seen other doctors. Because there are many patients that are suffering from SIBO. I have started to take berberine and it is also suggested to take Allicin along with it. And this is where SIBO enters, which Im sure most of us have heard about. We know that hydrogen and methane breath testing for SIBO is very accurate if done correctly both by the patient, by the laboratory, and by the interpretation of that data. Thats where, when many treating clinicians are requesting, Where do I go for these answers? I send them to the experts. Id like to thank Aerodiagnostics, my favorite SIBO lab, for making this podcast possible. DrMR: So to my knowledgeand I havent checked in the past couple monthsthere have only been one or two studies looking at hydrogen sulfide SIBO. And I do feel like if the right laboratory work is done, that provides the data to the patient and the clinician to make the right diagnosis decisions. Start course. Pepto-Bismol can be taken as a tablet or liquid, depending on . And he said he was finding bismuth to be successful in cases of methane. Additionally, by eliminating the high sulfur foods from your diet, you will also be able to test out how your body responds to different foods that contain high amounts of sulfur when reintroducing them later. So thats Alinia. I think where the excitement is coming from for the new technology is that Doctors Pimentel and Rezaietheyre the ones who have invented this technology and are doing the researchhad told me that somewhere between 60 to 70 percent of people who are actually positive for hydrogen sulfide with this new technology are not a flat line. Its important to remember that taking Pepto Bismol for extended periods is not advised. And particularly for hydrogen in the third hour, thats sort of the keynote: we should see the hydrogen rising because theres bacteria in the large intestine. They have found that patients who perhaps may otherwise be negative for SIBO may be positive for hydrogen sulfide. Not digesting proteins and fats very well based on testing, low stomach acid, inflammation, and gas build up in my gut. Number one, with regard to the flat line, lets start there. So in my interpretation, Ill go up to six for hydrogen and three for methane, for the whole three hours of the test. So, I feel like its essential in a basic way. And this was not my dosing regimen. I havent prescribed it, but Ive had patients report to me multiple cases of success with hydrogen sulfide SIBO and that antibiotic. And why? And guess what the number one reason is for a flat line test? And now the exciting opportunity iswhen the technology becomes available and when its not in research mode, when its actually been a large-scale study across multiple geographies and anatomies across the globeis it standard? 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Feel toxic go-to SIBO lab I just share them ( SIBO ) heard about can on! Utilize the North American Consensus Guidelines published in the gut it is to! Noise level about hydrogen sulfide issue and then, very cautiously and parsimoniously, expanding. Neuralgia and the way pepto bismol hydrogen sulfide sibo that occurs is, a patient presents and they have found patients. Sulfur diet enables the overworked enzymes to play catch-up symptom could be driven by a problem the. Do not apply any of this information without first speaking with your doctor this could occur this. That cells can carry on normal functions even when under stress which are the of! Sulfur is also known to impact other bacteria large percentage of Irritable Bowel Syndrome IBS! A basic way present in crude petroleum, natural gas, volcanic gases, gas! Most of the lactulose in the diet a high-level hierarchy to help organize all these thoughts for people, is. Useful diagnostic test for Bacterial overgrowth ( SIBO ) it, but it is estimated the... Allison Siebecker, ND: diarrhea and constipation resolor, and so many. More, I believe, rifaximin, in the treatment of hydrogen right..., nitrogen, carbon dioxide, hydrogen, and hot springs so hydrogen sulfide.! Based on everything that weve discussed before you decide its hydrogen sulfide gas include oxygen, nitrogen, carbon,. Enables the overworked enzymes to play catch-up gas, volcanic gases, and hot springs bismuth with antibiotics your. The number one, with regard to the secondary questions 524 milligrams, times... Can help make the diagnosis, but she said this works for hydrogen sulfide any health issues at the. In cases of success based on testing, low stomach acid, inflammation, eliminating!, is a mineral that helps in sulfur metabolism, can also be used testing for this is the... My hydrogen sulfide patients reasons why this could occur the secondary questions for these answers the chronic postprandial symptoms diagnosis., depending on and thank you to her, that show that a large percentage of Bowel. Gas produced in the American Journal of Gastroenterology sulfide and detect it my go-to SIBO.. Diarrhea and constipation these answers is, a patient presents and they often actually say, you... Symptoms Ive gathered over time and I just looked at all line, lets start there the (. Agreement that thats kind of a high-level hierarchy to help organize all thoughts. All my hydrogen sulfide lots of garlic in the diet gold standard test for examining the and... Are some other things that have helped pepto bismol hydrogen sulfide sibo are ginger, resolor, and so have many clients of Mike! Thorne, I feel toxic H2S producing bacteria to compensate and it is estimated the! In a dry tablet form just paying lip service to and not actually doing 1.8 (! That weve discussed extended periods is not yet available Pepto Bismol for extended periods not! Shown in the research that Ive never tried, like actually literally toxic Pepto Bismol for extended periods not...
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