Munday JS, James KA, Fray LM, et al. Salem, S., Salahi, M., Mohseni, M., Ahmadi, H., Mehrsai, A., Jahani, Y., and Pourmand, G. Major dietary factors and prostate cancer risk: a prospective multicenter case-control study. Garlic might also increase the risk of bleeding and cause allergic reactions in some people. Brosche, T., Platt, D., and Dorner, H. The effect of a garlic preparation on the composition of plasma lipoproteins and erythrocyte membranes in geriatric subjects. Liu, C. T., Su, H. M., Lii, C. K., and Sheen, L. Y. Summary, evidence report/technol assessment: no 20. 19 Nov. 2002. View abstract. Z., and Li, B. Allitridum mimics effect of ischemic preconditioning by activation of protein kinase C. Acta Pharmacol.Sin. Cox MC, Low J, Lee J, et al. These side effects are often worse with raw garlic. JAMA 1998;279:1900-2. Modulation of lipid profile by fish oil and garlic combination. View abstract. Garlic may increase the risk of bleeding. Int J Immunopharmacol. 2009;23(4):579-581. Superko HR, Krauss RM. J Natl.Cancer Inst. Lancet 4-27-1996;347(9009):1195. Ku DD, Abdel-Razek TT, Dai J, and et al. To avoid the potential of developing skin lesions where you came in contact with the garlic, they recommend wearing protective gloves. The Iowa Womens Health Study, which included more than 40,000 women aged between 55 and 69, found that garlic consumption may decrease the risk of developing colon cancer. View abstract. Chemical burn caused by topical application of garlic under occlusion. J Nutr 2006;136(3 Suppl):793S-795S. Garlic oil and Helicobacter pylori infection. View abstract. Nutrition Research 1987;7:139-149. Regulation of oxidative stress-mediated apoptosis by diallyl sulfide in DMBA-exposed Swiss mice. View abstract. In: Ohigashi H, Osawa T, Terao J, and et al. View abstract. View abstract. View abstract. Takasu, J., Uykimpang, R., Sunga, M. A., Amagase, H., and Niihara, Y. Koscielny J, Klussendorf D, Latza R, et al. View abstract. Ashraf R, Khan RA, Ashraf I, Qureshi AA. J Allergy Clin Immunol 1997;100:734-8. diarrhea. View abstract. View abstract. Monitor your blood pressure closely. View abstract. 2004;15(6):373-377. Ide N, Lau BH. J Nutr. van der Walt, A., Lopata, A. L., Nieuwenhuizen, N. E., and Jeebhay, M. F. Work-related allergy and asthma in spice mill workers - The impact of processing dried spices on IgE reactivity patterns. View abstract. A meta-analysis. Risk factors for oesophageal cancer in northeast China. Hoshino, T et al. Hirsch, K., Danilenko, M., Giat, J., Miron, T., Rabinkov, A., Wilchek, M., Mirelman, D., Levy, J., and Sharoni, Y. Effect of garlic powder tablets on blood lipids and blood pressure-a six month placebo controlled, double blind study. Am J Hypertens. Postgrad Med J. View abstract. View abstract. Anibarro B, Fontela JL, De La Hoz F. Occupational asthma induced by garlic dust. Kockar, C., Ozturk, M., and Bavbek, N. Helicobacter pylori eradication with beta carotene, ascorbic acid and allicin. View abstract. Garlic intake lowers fasting blood glucose: meta-analysis of randomized controlled trials. Med Lett Drugs Ther 1997;39:9-10. Ahmadi N, Nabavi V, Hajsadeghi F, et al. Forsch.Komplementmed. Effect of garlic powder on C-reactive protein and plasma lipids in overweight and smoking subjects. 1987;70 Suppl 2:223-227. Reduction in elevated blood lipids in hospitalised patients by a standardised garlic preparation. Bagga, S., Thomas, B. S., and Bhat, M. Garlic burn as self-inflicted mucosal injury--a case report and review of the literature. Prostaglandins Leukot Essent Fatty Acids 1998;58:257-63.. View abstract. View abstract. Randomized double-blind factorial trial of three treatments to reduce the prevalence of precancerous gastric lesions. He has been in the digital media field for over eight years. J Antimicrob.Chemother. Ide N, Nelson AB, and Lau BHS. View abstract. The effect of a garlic supplement on the pro-inflammatory adipocytokines, resistin and tumor necrosis factor-alpha, and on pain severity, in overweight or obese women with knee osteoarthritis. Nature 4-6-2000;404(6778):542. View abstract. Therapiewoche 1988;38:3885-3890. Vaginal yeast infections (thrush): What helps? View abstract. Tsai PB, Harnack LJ, Anderson KE, and et al. 1990;29(1):75-76. Am J Med 1993;94:632-5. Evid Based Complement Alternat Med 2021;2021:6667453. Garlic compounds protect vascular endothelial cells from oxidized low density lipoprotein-induced injury. However, some studies have suggested that raw garlic may be more effective than the cooked version, while garlic supplements are the most effective. 2012;36(5):439-444. Effect of garlic on blood pressure: a systematic review and meta-analysis.BMC cardiovascular disordersvol. View abstract. Effects of garlic (Allium sativum L.) supplementation on cytochrome P450 2D6 and 3A4 activity in healthy volunteers. Atherosclerosis 1998;139:333-339. 2007;14(7-8):447-451. View abstract. Effect of garlic on total serum cholesterol. 2007;86(6):1754-1764. Seuri, M., Taivanen, A., Ruoppi, P., and Tukiainen, H. Three cases of occupational asthma and rhinitis caused by garlic. Siegel G, Klubendorf D. The anti-atherosclerotic effect of Allium sativum: Statistics re-evaluated. Sivam, G. P. Protection against Helicobacter pylori and other bacterial infections by garlic. View abstract. Dehghani F, Merat A, Panjehshahin MR, Handjani F. Healing effect of garlic extract on warts and corns. Nahas, R. and Balla, A. Complementary and alternative medicine for prevention and treatment of the common cold. ", A.A. Myneni et al., Cancer Epidemiology, Biomarkers & Prevention: "Raw Garlic Consumption and Lung Cancer in a Chinese Population. Cavagnaro et al., Journal of Agricultural and Food Chemistry, "Effect of Cooking on Garlic (Allium sativum L.) Antiplatelet Activity and Thiosulfinates Content. Rashes on the Skin 8. Z Phytother 1984;5:938-942. In that study, participants who consumed garlic 5 or more times a week had the greatest reduction, while those who consumed it less than once a week had the highest risk of gastric cancer. Recent studies with a standardized dry garlic powder substance]. View abstract. Br J Clin Pract Symp Suppl 1990;69:7-11. Belman, S. Onion and garlic oils inhibit tumor promotion. 2003;133(7):2171-2175. Groppo, F. C., Ramacciato, J. C., Simoes, R. P., Florio, F. M., and Sartoratto, A. Antimicrobial activity of garlic, tea tree oil, and chlorhexidine against oral microorganisms. Scand.J Urol.Nephrol. 2006;50(5):1731-1737. View abstract. Oral Health Prev.Dent. Garlic is one of those foods that people love to eat Click here for additional information. You WC, Zhang L, Gail MH, et al. Pediatr.Emerg.Care 1987;3(4):258-260. 2004;92(4):701-706. Arzneimittelforschung 1999;49:544-7. Clin Cancer Res 2006;12:4636-40. Tanaka, S., Haruma, K., Kunihiro, M., Nagata, S., Kitadai, Y., Manabe, N., Sumii, M., Yoshihara, M., Kajiyama, G., and Chayama, K. Effects of aged garlic extract (AGE) on colorectal adenomas: a double-blinded study. Garlic has been used safely for up to 7 years. Rotzsch W, Richter V, Rassoul F, Walper A. 2020;13:2389-2397. 2012;31(3):337-344. Ried K, Toben C, Fakler P. Effect of garlic on serum lipids: an updated meta-analysis. View abstract. View abstract. Garlic.National Center for Complementary and Integrative Health, U.S. Department of Health and Human Services. Arch Pediatr Adolesc Med 1998;152:1089-94. Cancer 6-1-1993;71(11):3575-3581. Journal of Medical Council of Islamic Republic of Iran (J MED COUNC ISLAMIC REPUB IRAN) 2005;23(3):319. A commentary on the effects of garlic extraction and formulation on product composition. Excess intake may cause loss of appetite. View abstract. View abstract. So far, studies show little evidence of toxicity from allicin. Prostaglandins Leukot Essent Fatty Acids 1996;54(3):183-186. , may cause or aggravate hyphema. Andrianova, I. V., Ionova, V. G., Demina, E. G., Shabalina, A. View abstract. Though it doesnt directly cause a migraine headache, it activates the process responsible for it. View abstract. 1998;14(8):737-747. Experientia 2-15-1996;52(2):115-120. Aged garlic extract reduces left ventricular myocardial mass in patients with diabetes: A prospective randomized controlled double-blind study. 2002;132(2):168-171. Rockville, MD. J Nutr. Phytother.Res. Wang Y, Wu Y, Fu P, et al. Contact Dermatitis 1997;37:70-7. 8-1-2010;75(6):C549-C558. 16 Jun. 2011;38(3):280-282. Plast Reconstr Surg 1995;95:213. Am J Epidemiol 1994;139:1-15. Food Sci Nutr 2021;9(7):3556-3562. Sahebkar A, Serban C, Ursoniu S, Banach M. Effect of garlic on plasma lipoprotein(a) concentrations: A systematic review and meta-analysis of randomized controlled clinical trials. Trop.Doct. View abstract. View abstract. Warfarin and garlic. Changes in platelet function and susceptibility of lipoproteins to oxidation associated with administration of aged garlic extract. Prev.Med 2004;39(5):985-991. View abstract. Medicine (Baltimore). Nutr Cancer 1997;27:186-91. J Nutr. Ried K, Frank OR, Stocks NP. View abstract. J Nat Toxins. Indian J Physiol Pharmacol 1979;23(3):211-214. Certain women insert garlic cloves into the vaginas as a remedy to treat vaginal yeast infections. Some side effects such as heartburn, diarrhea, and abdominal discomfort might occur when a person consumes more than 5 grams (g) of it per day. View abstract. Parish, R. A., McIntire, S., and Heimbach, D. M. Garlic burns: a naturopathic remedy gone awry. View abstract. Xiong XJ, Wang PQ, Li SJ, Li XK, Zhang YQ, Wang J. Garlic for hypertension: A systematic review and meta-analysis of randomized controlled trials. Hassan, Z. M., Yaraee, R., Zare, N., Ghazanfari, T., Sarraf Nejad, A. H., and Nazori, B. Immunomodulatory affect of R10 fraction of garlic extract on natural killer activity. Senapati SK, Dey S, Dwivedi SK, Swarup D. Effect of garlic (Allium sativum L.) extract on tissue lead level in rats. Ashraf, R., Khan, R. A., and Ashraf, I. Garlic (Allium sativum) supplementation with standard antidiabetic agent provides better diabetic control in type 2 diabetes patients. Get emergency medical help if you have any of these signs of an allergic reaction while taking garlic: hives; difficult breathing; swelling of your face, lips, tongue, or throat. U.S. STD Cases Increased During COVIDs 2nd Year, Pesticide in Produce: See the Latest Dirty Dozen, Having A-Fib Might Raise Odds for Dementia, New Book: Take Control of Your Heart Disease Risk, MINOCA: The Heart Attack You Didnt See Coming, Health News and Information, Delivered to Your Inbox, Becoming a Vegetarian: Foods to Choose From. Ahmadi, N., Tsimikas, S., Hajsadeghi, F., Saeed, A., Nabavi, V., Bevinal, M. A., Kadakia, J., Flores, F., Ebrahimi, R., and Budoff, M. J. View abstract. Does garlic elevate blood pressure levels? 1972;87(1):6-9. Am J Gastroenterol 1999;94:1200-2. Clin Res Hepatol Gastroenterol 2012;36(6):e134. View abstract. BMJ Case Rep 2014. Pharmacology 2003;67(3):113-117. *Percent Daily Values are based on a 2,000 calorie diet. According to Jesse, Garlic is not stronger than antibiotics, even though garlic has some antibiotic properties., Jesse agrees and says, Garlic contains certain compounds that can affect the smell of your urine.. This typically ranges from 1.1% to 1.3%. Buhshan S, Sharma SP, Singh SP, and et al. Bimmermann A, Weingart K, and Schwartzkopff W. Allium sativum: Studie zur Wirksamkeit bei Hyperlipoproteinamie. Shakeel, M., Trinidade, A., McCluney, N., and Clive, B. Complementary and alternative medicine in epistaxis: a point worth considering during the patient's history. Desai G, Schelske-Santos M, Nazario CM, et al. Jeyaraj S, Shivaji G, and Jeyaraj SD. J Nutr 2001;131(6):1662-1667. View abstract. View abstract. Evidence from the German Association of General Practitioners' multicentric placebo-controlled double-blind study. Microbes Infect 1999;1:125-9. Kim H, Keum N, Giovannucci EL, Fuchs CS, Bao Y. Garlic intake and gastric cancer risk: results from two large prospective US cohort studies. View abstract. View abstract. Common side effects (especially when eating raw garlic) may include: unpleasant breath or body odor; heartburn, burning in your mouth or throat; nausea, Taking garlic along with medications that lower blood pressure might cause blood pressure to go too low. Raw garlic consumption is inversely associated with prehypertension in a large-scale adult population. View abstract. The potential application of Allium sativum (garlic) for the treatment of bladder cancer. J Gen.Microbiol. Consumption of aqueous garlic extract leads to significant improvement in patients with benign prostate hyperplasia and prostate cancer. View abstract. Lipids 1996;31:1269-76. 2009;89(1):257-264. Pedraza-Chaverr, Jos, et al. View abstract. Capraz, M., Dilek, M., and Akpolat, T. Garlic, hypertension and patient education. A., Prianishnikov, V. V., Kunnova, L. M., Rabinovich, E. A., and Orekhov, A. N. [Use of allicor to lower the risk of myocardial infarction]. Zhou XF, Ding ZS, Liu NB. View abstract. Potential value of plants as sources of new antifertility agents I. J Pharm Sci 1975;64:535-98. 2015;22(3):352-61. View abstract. Xie, W. and Du, L. Diabetes is an inflammatory disease: evidence from traditional Chinese medicines. You WC, Blot WJ, Chang YS, et al. Nature 10-14-1999;401(6754):629. A controlled clinical study. View abstract. Li, M., Ciu, J. R., Ye, Y., Min, J. M., Zhang, L. H., Wang, K., Gares, M., Cros, J., Wright, M., and Leung-Tack, J. Antitumor activity of Z-ajoene, a natural compound purified from garlic: antimitotic and microtubule-interaction properties. Naganawa, R., Iwata, N., Ishikawa, K., Fukuda, H., Fujino, T., and Suzuki, A. Inhibition of microbial growth by ajoene, a sulfur-containing compound derived from garlic. View abstract. Xu S, Heller M, Wu PA, Nambudri VE. View abstract. Rahmy, T. R. and Hemmaid, K. Z. Prophylactic action of garlic on the histological and histochemical patterns of hepatic and gastric tissues in rats injected with a snake venom. Br.J Dermatol. Dillon, S. A., Lowe, G. M., Billington, D., and Rahman, K. Dietary supplementation with aged garlic extract reduces plasma and urine concentrations of 8-iso-prostaglandin F(2 alpha) in smoking and nonsmoking men and women. 2009;(3):CD006206. Effect of garlic on normal blood cholesterol level. Effect of garlic essential oil in 97 patients hospitalized with covid-19: A multi-center experience. Irritation of the Skin 5. View abstract. J Investig Allergol Clin Immunol. View abstract. A case report. Bruynzeel DP. Ruocco, V., Brenner, S., and Lombardi, M. L. A case of diet-related pemphigus. Effect of topical garlic on wound healing and scarring: A clinical trial. 2003;85(1):139-144. Heart 2000;83(suppl 2):A4. Garlic Prevents Hypertension Induced by Chronic Inhibition of Nitric Oxide Synthesis.Life Sciences, Pergamon, 25 Feb. 1998. View abstract. Vopr.Onkol. Life Sci. This is not a complete list of side effects and others may occur. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Choudhary PR, Jani RD, Sharma MS. Effect of raw crushed garlic (Allium sativum L.) on components of metabolic syndrome. Foster BC, Foster MS, Vandenhoek S, et al. 2006;45(10):1161-1163. Black or bloody stool. German, K., Kumar, U., and Blackford, H. N. Garlic and the risk of TURP bleeding. View abstract. View abstract. Contact Dermatitis 1988;18(3):179-181. 1988;134 ( Pt 11):2917-2924. Of Islamic Republic of Iran ( J MED COUNC Islamic REPUB Iran ) 2005 ; 23 ( Suppl. 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